CLL Vocabulary Lesson

There are many words I use in posts here that I never used prior to CLL entering my life. May this glossary help understanding some of the alphabet soup of clinical terms that frequently appear here.

Anemia [n]: A pathological deficiency in the oxygen-carrying component of the blood, measured in unit volume concentrations of hemoglobin, red blood cell volume, or red blood cell number.
Antibody [n]: Any of various proteins produced in the blood in response to the presence of an antigen. By becoming attached to antigens on infectious organisms antibodies can render them harmless or cause them to be destroyed See also immunoglobulin
Bone Marrow Biopsy (BMB) [n]: The removal of a sample of bone marrow and a small amount of bone through a large needle. Two samples are taken. The first is bone marrow by aspiration (suction with a syringe). The second is a core biopsy to obtain bone marrow along with bone fibers. After the needle is removed, this solid sample is pushed out of the needle with a wire. Both samples are examined under a microscope to examine the cells and the architecture of the bone marrow.
Chemistry Screen [n]: A chemistry screen is a blood test that measures the levels of several substances in the blood.

  • Albumin.
  • Alkaline Phosphatase.
  • Alanine Aminotransferase (ALT).
  • Aspartate Aminotransferase (AST).
  • Bilirubin (total and direct).
  • Blood Glucose.
  • Blood Urea Nitrogen.
  • Calcium (Ca) in Blood.
  • Carbon Dioxide (Bicarbonate).
  • Chloride (Cl).
  • Cholesterol and Triglycerides Tests.
  • Creatinine and Creatinine Clearance.
  • Gamma-Glutamyl Transferase (GGT).
  • Lactate Dehydrogenase.
  • Phosphate in Blood.
  • Potassium (K) in Blood.
  • Sodium (Na) in Blood.
  • Total Serum Protein.
  • Uric Acid in Blood.

CBC (Complete Blood Count) [n]: A diagnostic test which measures:

  • The number of red blood cells (RBC count)
  • The number of white blood cells (WBC count)
  • The total amount of hemoglobin in the blood
  • The fraction of the blood composed of red blood cells (hematocrit)

CT Scan [n]: A computed tomography (CT) scan is an imaging method that uses x-rays to create pictures of cross-sections of the body.
Immunoglobulin [n]: Any of a group of large glycoproteins that are secreted by plasma cells and that function as antibodies in the immune response by binding with specific antigens. There are five classes of immunoglobulins: IgA, IgD, IgE, IgG, and IgM.
Lymphadenopathy [n]: Chronically swollen lymph nodes.
Lymphocyte [n]: Any of the nearly colorless cells found in the blood, lymph, and lymphoid tissues, constituting approximately 25 percent of white blood cells and including B cells, which function in humoral immunity, and T cells, which function in cellular immunity.
Lymphocytosis [n]: An abnormal increase in the number of lymphocytes in the blood.
Monoclonal Antibody [n]: Any of a class of antibodies produced in the laboratory by a single clone of cells or a cell line and consisting of identical antibody molecules
Neutropenia [n]: An abnormal decrease in the number of neutrophils in the blood.
Splenomegaly [n]: Enlargement of the spleen.
Thrombocyte (also known as platelet) [n]: A minute cell occurring in the blood of vertebrates and involved in clotting of the blood
Thrombocytopenia [n]: An abnormal decrease in the number of blood platelets.

Please let me know if I’ve missed anything.

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